To my knowledge, Semblage is currently only being tested on a few different systems across a few users. It would be helpful to have the release packages tested by more users on a variety of systems. Semblage does require OpenGL ES 3.0 support, which should be available on most Intel and AMD computers from the last decade that support 3D graphics accelleration. The slowest processor Semblage will run on has not been found yet, as the graphics chipset is the most important part.
If you are interested in trying Semblage out on your Windows or Linux system, the following links should help. You can report issues on GitHub if you have an account there, or simply report back here.
Mac OS is currently not supported because of this issue.